Plexopatía braquial bilateral aguda tras una cirugía abdominal que imita al síndrome del ‘hombre en el barril’ / Acute bilateral brachial plexopathy after abdominal surgery mimicking a man-in-the barrel syndrome

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[The prevalence of clotting disorders in a series of cases of thrombosis of the cerebral venous sinuses]. / Prevalencia de los trastornos de la coagulación en una serie de trombosis de senos venosos cerebrales.

INTRODUCTION: Cerebral venous sinus thrombosis (CVSTs) constitutes an infrequent location of the venous thrombotic disease. It is caused by diverse factors, although up to 35% of the CVSTs can remain without aetiologic diagnosis. Coagulation disorders have been involved in up to 75% of the CVSTs. AIM. To describe the prevalence of coagulation disorders in a consecutive series of CVSTs. PATIENTS AND METHODS: We performed a retrospective revision of the clinical history of all patients with CVST admitted in our service between January, 1st 1995 and December, 31st 2005. The thrombophilic study was carried out a posteriori in whatever individual who lacked it. RESULTS: We studied twenty-one cases (7 men and 14 women), within an age range of 16-69 years old (corresponding to an average of 35,4 +/- 14,4 years old). The thrombophilic study was carried out in eighteen patients. Five (27,7%) presented some hereditary coagulation disorder; in four of them, a hormonal cause coexisted. CONCLUSION: Recent advances in the diagnostic procedures for the detection of thrombophilias and hereditary prothrombotic mutations have enabled the specialists to be more precise in the aetiologic diagnosis of suspected CVST. Even so, the apparent cause for a high percentage of patients with CVST has not been found yet.

Prevalencia de los trastornos de la coagulación en una serie de trombosis de senos venosos cerebrales / The prevalence of clotting disorders in a series of cases of thrombosis of the cerebral venous sinuses

La trombosis de senos venosos cerebrales (TSVC) constituye una localización infrecuente de la enfermedadvenosa trombótica. En su aparición están implicados diversos factores, aunque hasta un 35% de las TSVC puedequedar sin diagnóstico etiológico. Los trastornos de coagulación se han implicado hasta en un 75% de las TSVC. Objetivo.Describir la prevalencia de los trastornos de la coagulación en una serie de TSVC consecutivas. Pacientes y métodos. Se realizó una revisión retrospectiva de todas las historias clínicas de los pacientes ingresados con una TSVC en el Servicio de Neurologíadel Hospital Universitario de Gran Canaria Doctor Negrín, entre el 1 de enero de 1995 y el 31 de diciembre de 2005. En todos los casos en los que no se hubiese realizado estudio de trombofilia se hizo a posteriori. Resultados. Se estudiaron 21 casos (7 varones y 14 mujeres), entre 16 y 69 años (edad media de 35,4 ± 14,4 años). Se realizaron 18 estudios de trombofilia.Se halló algún trastorno de la coagulación hereditario en cinco (27,7%), y en cuatro de ellos existía una causa hormonal.Conclusión. La mejora en los métodos diagnósticos para la detección de trombofilias y mutaciones protrombóticas hereditarias ha permitido aumentar la precisión en el diagnóstico etiológico de las TSVC. Aun así, un porcentaje elevado de pacientes con TSVC sigue sin tener una causa aparente para ésta

Cerebral venous sinus thrombosis (CVSTs) constitutes an infrequent location of the venous thromboticdisease. It is caused by diverse factors, although up to 35% of the CVSTs can remain without aetiologic diagnosis. Coagulation disorders have been involved in up to 75% of the CVSTs. Aim. To describe the prevalence of coagulation disorders in a consecutive series of CVSTs. Patients and methods.We performed a retrospective revision of the clinical history of all patientswith CVST admitted in our service between January, 1st 1995 and December, 31st 2005. The thrombophilic study was carried out a posteriori in whatever individual who lacked it. Results. We studied twenty-one cases (7 men and 14 women), within an age range of 16-69 years old (corresponding to an average of 35,4 ± 14,4 years old). The thrombophilic study was carried outin eighteen patients. Five (27,7%) presented some hereditary coagulation disorder; in four of them, a hormonal cause coexisted. Conclusion. Recent advances in the diagnostic procedures for the detection of thrombophilias and hereditary prothrombotic mutations have enabled the specialists to be more precise in the aetiologic diagnosis of suspected CVST. Evenso, the apparent cause for a high percentage of patients with CVST has not been found yet